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Causes and treatment of hormonal failure in men

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The human hormonal system provides him with normal growth, development and reproductive function. In the event of a malfunction of this system, the patient develops a wide variety of deviations.

Hormonal failure in women has its own characteristics, the "stronger sex" - others. Let us consider in more detail the symptoms of hormonal failure in men and methods of treatment of this phenomenon.

Hormonal failure in men: causes

Contribute to the development of hormonal failure in men can following factors:

1. Chronic physical exhaustion.

2. Strong psycho-emotional overstrain (stress, frequent agitation, etc.).

3. Constant lack of sleep.

4. Tendency to depression.

5. Genetic predisposition of a person to hormonal disruption in the body.

6. Chronic course of various infectious diseases.

7. Defeat acute viral pathologies.

8. Acceptance of narcotic substances.

10. Work in conditions with toxic effects on the body (poisoning household chemicals, etc.).

11. Improper treatment with hormone drugs.

12. The effects of household chemicals (powders, shampoos, etc.) have a bad effect on testosterone production in men. This inhibits the work of the sex glands and increases the likelihood of hormonal disruption.

13. Congenital or acquired diseases of the adrenal glands, testicles or pituitary gland.

14. Various diseases of the endocrine system (especially diabetes).

15. Living in an unfavorable ecological environment.

16. Frequent alcohol intake. This is especially true of regular beer consumption. The fact is that this drink contains analogues of female sex hormones, so they suppress the natural production of testosterone in men, replacing it with female hormones. As a direct consequence of this, a person increases the fat mass, the breast may increase and there is a general failure in the hormonal system.

18. Effect of radiation.

19. Development of oncological pathologies.

20. Old age of the man. Hormonal imbalance in this case is justified by a natural decrease in the production of androgens, which occurs due to a decrease in the cells of the sex glands.

Moreover, the state of the liver and kidneys plays a great role in the development of hormonal disruption in men, since the exchange of sex hormones and their further elimination from the body depend on their well-coordinated work. If these organs function poorly, then the person becomes more prone to hormonal failure.

It is important to know that hormonal indicators may vary slightly during the day. This is explained by the purely physiological construction of body systems. This phenomenon does not always indicate possible pathology.

Hormonal failure in men: symptoms and signs

There are the following features of the hormonal failure in men:

1. If this condition has developed in adolescence, then the patient may experience early sexual development, or vice versa - delayed development of the reproductive system.

2. When a hormonal failure occurs in men between the ages of twenty and forty, obesity, decreased libido and complete sterility can be observed. Also, all sorts of disorders in the nervous system (tendency to depression, irritability, drowsiness, and headaches) often develop.

3. Often there is rapid fatigability, apathy, lethargy, sharp fluctuations in mood.

4. With the appearance of this pathology at a more mature age, the patient may decrease self-esteem, panic attacks and tearing.

5. Sometimes a dramatic change in hormonal background can also affect the work of the reproductive system. In this case, the patient will feel pain when urinating, urinary incontinence. Also, with a decrease in testosterone production in humans, fat deposition can be observed in the female prototype, and the growth of hair on the face stops.

6. Pain, stiffness in the joints, heaviness in movement and osteoporosis may appear in the locomotor system.

Also distinguish the following additional signs of hormonal failure, which can identify this pathology:

1. Decrease in physical endurance.

2. Dryness of the skin.

3. Increased blood sugar levels.

4. Hair fragility.

5. Increased sweating.

6. Trembling in limbs.

7. Constant fatigue.

8. Blood pressure jumps.

9. Sensation of hoarseness.

10. Increased bone fragility.

11. The appearance of irregularities in the cardiovascular system.

Hormonal failure in men: diagnosis and treatment

When the first signs of hormonal failure appear, a man is advised to consult a doctor as soon as possible and begin diagnosis. Traditionally, the doctor will prescribe general clinical blood and urine tests, as well as tests for the level of hormones in the body.

Additionally, the patient may be assigned to examinations of the cardiovascular system, abdominal ultrasound, ECG, examination of the sexual and endocrine systems. In general, it is advisable to conduct a full examination of the body in order to be able to timely detect any pathologies associated with hormonal disruption.

The methods and tactics of general therapy will largely depend on the results of the tests obtained, the patient's age, the presence of chronic diseases, as well as the root cause, which caused a hormonal failure. Thus, the course of treatment is selected for each patient individually.

Traditional treatment of hormonal failure has the following features:

1. If this condition has developed in a person at a young age, then therapy should be aimed at normalizing the natural work of the sex glands, as well as improving the functioning of the organs that are responsible for the exchange of sex hormones.

In this case, the patient needs to prescribe special drugs to normalize the work of the liver, thyroid gland, and the pituitary gland. As an additional support, vitamins are also sometimes prescribed.

2. If a hormonal imbalance developed in an elderly patient, then, most likely, he will be prescribed life-long medication with testosterone. In fact, there is nothing terrible in this, since these drugs will maintain the optimal level of hormones that a person needs for the normal functioning of the body.

3. If a hormonal failure has caused cancer, then the patient may be given chemotherapy and surgical treatment. In this case, the overall treatment will largely depend on the specific location of the tumor and its neglect.

4. As a drug therapy, the patient may be prescribed hormone-containing drugs (Andriol, Nebido).

In addition, it is very important for patients during the treatment period to adhere to such medical recommendations:

1. Observe diet food (refuse fatty, fried, sweet, flour and alcohol).

2. Avoid stress and do not worry.

3. It is desirable for the patient to stay at home or in a hospital under medical supervision for the period of treatment.

4. Minimize exercise.

After the end of therapy, the patient may also be assigned a sanatorium recovery.

The success of treatment will be determined by the results of tests. Also, with a favorable course of therapy, the patient will gradually begin to notice improvements in his condition: sleep will return to normal, strength will increase, mood will improve, etc.

Hormonal failure in men: features of treatment, prevention and consequences

In the absence of timely therapy for hormonal failure, men may develop such complications:

3. Violations in the central nervous system.

5. The risk of heart attack.

To reduce the risk of developing this pathology, men are advised to follow these tips:

1. Have a full sleep and rest.

2. Avoid strong nerves and stress.

3. Eat right. The diet should be well balanced and rich in vitamins.

4. Promptly consult a doctor when the first signs of hormonal failure.

5. Avoid severe physical fatigue.

6. Timely treat any diseases that can lead to hormonal failure.

7. Refrain from smoking, drinking and taking drugs.

What hormones are present in the male body?

Hormones affect the operation of virtually all systems. Such substances are synthesized by the body and are divided into three large groups:

  1. Androgens are male hormones, and the most important is testosterone, which determines the male sex characteristics: body hair growth, broad shoulders, relief muscles, narrow pelvis. Also, the hormone is involved in the reproductive system - provides an erection and ejaculation.
  2. Surprisingly, in the male body there are also female hormones, for example, estrogen, which is responsible for sexual desire, the normal state and elasticity of the skin, preservation of the structure of bone tissue, and metabolism. With increasing levels of appearance begins to change in the direction of the female type.
  3. Hormones of the endocrine glands, which include insulin, thyroid gland, thyroxin, and triiodothyronine. They take part in metabolic processes, have a direct effect on the general hormonal background.

When the imbalance of hormones is disturbed, failures occur, which affect the functioning of the whole organism. If not to eliminate violations in time, it can lead to serious consequences.

Signs of failure

To identify the hormonal failure of a man can be on the following grounds:

  • in adolescence may delay sexual development or, on the contrary, the acceleration of maturation,
  • decreased physical activity, decreased stamina, general weakness, low muscle tone,
  • unreasonable weight gain (moreover, the volume of not only the abdomen, which is typical for men, but also of all parts of the body, including arms and legs, usually increases),
  • decrease or complete absence of sexual desire,
  • problems with potency, the lack of a full erection, weak ejaculation,
  • fatigue, drowsiness, chronic fatigue, depression, apathy,
  • irritability, increased nervous irritability, disturbing thoughts,
  • mood swings, pessimistic thoughts, depression, reduced self-esteem,
  • slower growth of hair on the chest and face, baldness,
  • dizziness, headache,
  • reduced mobility of joints, pain in the limbs, increased bone fragility,
  • deterioration of the skin: peeling or, on the contrary, the appearance of oily shine,
  • brittleness, dull hair,
  • excessive sweating
  • changes in blood pressure,
  • heart rhythm disorders
  • timbre changes,
  • trembling in limbs.

Important! Not necessarily the manifestation of all the symptoms at the same time, often there are some, and alternately. But sometimes the signs are numerous and are observed almost constantly, significantly deteriorating the quality of life and negatively affecting all its spheres.

Possible reasons

Causes of hormonal disruptions in men can be very different:

  • Age. Failures can occur in adolescents due to hormonal changes or in older men due to the inevitable age-related extinction of sexual functions.
  • Inflammatory diseases of the reproductive organs, such as prostatitis, orchitis.
  • Postponed acute infections such as parotitis. Gilt, as people call the disease, is especially dangerous in childhood and adolescence, as it can lead to infertility.
  • Frequent and severe stress, emotional stress.
  • Excessive intense exercise during training, hard work.
  • Bad habits: alcohol abuse, drug intake.
  • Uncontrolled use of hormones, such as steroids for the growth of muscle mass.
  • Hereditary predisposition Often, failures are observed in members of the same family or close relatives.
  • Endocrine diseases: thyrotoxicosis, hypothyroidism, diabetes mellitus.
  • Diseases of the kidneys, liver. These organs are involved in the processing of hormones synthesized by the body.
  • Pathologies or diseases of the endocrine glands, which include the pituitary, adrenal glands, hypothalamus.
  • Living or working in adverse conditions: exposure to poisons and toxins, radiation exposure, poor ecology.
  • Overweight, obesity.
  • Malnutrition: eating sweets in large quantities, fatty and high-calorie foods.
  • Some oncological diseases.

Diagnostic measures

For diagnosis, the doctor may prescribe blood tests for hormones (testosterone, thyroid) and glucose levels, as well as biochemical and general. For the correct diagnosis, ultrasound examinations of the abdominal cavity and thyroid gland, ECG are recommended. In some cases, magnetic resonance or computed tomography, x-rays may be required.

How to treat hormonal failure in men? Therapy should be aimed at eliminating the causes, so you should begin to act after a full examination and diagnosis.

Treatment, depending on the mechanism of development of failure and associated health problems, may include the following areas:

  1. When failures are often prescribed hormones, the selection of which is carried out taking into account the level of hormones. It is important to strictly observe the dosage and regimen.
  2. Normalization of weight. To do this, you need to establish nutrition, eliminating from the diet fatty, sweet, fried, flour. Useful vegetables, meat, seafood, fruits, fish, low-fat milk and dairy products, cereals, berries, nuts, legumes. Physical activity is important, so a man should go to the gym or at least do exercises at home, move more. But to train too intensely should not.
  3. Normalization of the work of internal organs: liver, thyroid, kidney. Hepatoprotectors, choleretic agents are useful for the liver. In diseases of the thyroid gland iodine preparations are prescribed, hormone replacement therapy. In pathologies of the kidneys diuretics may be recommended.
  4. When neoplasms shows surgical intervention. Oncological diseases require a course of chemo, radiation therapy.
  5. Improving living conditions, preventing stress.
  6. Folk remedies. You can drink a third cup three times a day of carrot or celery juice. Useful infusions and decoctions of medicinal plants: knotweed, wormwood, Potentilla goose, oregano, ginseng, hop.

Prevention

What to do to prevent hormonal disruptions? Observe preventive measures:

  • Compliance with the daily routine, proper rest.
  • Rejection of bad habits.
  • Balanced and healthy food.
  • Moderate training, normal physical activity.
  • Timely treatment to the doctor and scheduled examinations.
  • Avoiding stress.

Hormonal failure can adversely affect men's health. But now you can quickly identify and eliminate it with the help of a specialist.

Principles of a simple test for violations

To identify the symptoms of hormonal failure of men, you can use a simple test. It is only necessary to read the questions for each group of signs and select those that fit the specific situation. More than 3 matches can mean one of three types of male hormone failure:

Signs of hormonal failure

Hormonal disorders in men (cause)

Symptom group number 1

  • Weight reduction.
  • Loss of muscle mass
  • Reduced sexual desire.
  • Fast fatiguability,
  • lethargy.
  • Erectile dysfunction.

Testosterone imbalance is the most common type of hormonal disruption, in which the male hormones are produced by the testes in insufficient quantities.

Symptom group number 2

  • Enlarged prostate gland.
  • Hair loss on the body.
  • Baldness on the head.
  • Increased irritability.
  • Increased abdomen.
  • Weight gain
  • Breast augmentation (not muscle, but fat mass).

These symptoms may indicate that a man has female hormones in an excess of (after all, they are not only produced from the ovaries of women, but are also produced by the male body).

Symptom group number 3

  • Bad memory and attentiveness.
  • Deterioration of the skin.
  • The appearance of brown spots on the skin of the body.
  • Low pressure.
  • Decreased physical stamina.

Such symptoms may signal a deficiency of cortisol, a hormone produced by the adrenal glands.

Symptom group # 3

  • Low-grade fever (37-37.5 degrees), which lasts a long time and is poorly knocked off with drugs.
  • Heart rhythm disorders.
  • Hand shake.
  • Weakness in arms and legs.
  • Increased sweating.
  • Insomnia.
  • Mood swings.

These may be symptoms of thyroid malfunction. It is necessary to check with the endocrinologist.

Naturally, this simple test is not a universal and accurate means of determining hormonal imbalance. But with his help you can suspect the violation and go to the clinic to conduct a more accurate diagnosis.

Imbalance factors

Hormonal background in men deviates from the norm during puberty or, conversely, during the extinction of reproductive functionality.Almost no man can avoid this and is considered normal, because it is at these stages that the endocrine system, which is responsible for the production of hormones, is most sensitive to various external and internal factors. It is important to know how to avoid disruptions or how to deal with the symptoms of age-related imbalance.

Pathology may arise from stress and strong emotional experiences.

But a violation of the hormonal level can occur not only during puberty or aging. Sometimes, for various reasons, there is a decrease or a surge in male or female hormones that cause unpleasant and sometimes dangerous disorders. The cause of hormonal failure of men can be:

  1. Congenital abnormalities, genetic predisposition.
  2. Inflammation, oncology in the organs of the endocrine system.
  3. Infections affecting glands and organs responsible for the production of hormones (testicles, adrenal glands, thyroid, etc.).
  4. Excessive stress, strong emotional distress.
  5. Physical overload of the body.
  6. Bad ecology, radiation, poisoning.
  7. Improper diet, taking certain drugs.
  8. Abuse of alcohol, smoking.

Some of the listed reasons for a man can eliminate himself (for example, to normalize food or quit bad habits). But as for diseases, it is impossible to diagnose them on their own - a doctor’s help is needed.

Ways to fix the problem

There is no uniform tactic how to treat pathological hormonal changes in men. It all depends on the type of imbalance and the reason for the hormonal disruptions of men. For example, if the diagnosis reveals an active hormone-producing tumor, either chemotherapy or surgery will be prescribed. Inflammations and infections are treated with antibiotics.

In most cases, replacement therapy is prescribed, which involves taking drugs to compensate for the deficiency of male or female hormones. Sometimes replacement therapy will be temporary (treatment stops after the production of their hormones is restored).

If the failures in men are irreversible, then taking drugs with hormones will have a lifetime.

Restoration of hormonal levels in men also implies a number of preventive measures. In addition to drugs, patients are prescribed:

  • Physiotherapy.
  • Phytotherapy.
  • Vitamin therapy.
  • Spa treatment.
  • Physiotherapy.
  • Power adjustment.

Alone, these activities are not able to cure hormonal disruption, but in combination with the main medications help to quickly restore the desired level of hormones.

DISTURBANCE OF HORMONAL BACKGROUND IN MEN: SYMPTOMS

Hormonal disorders in men are usually manifested by one or more of the following symptoms.

The main male sex hormone testosterone (T) is responsible for muscle mass. When its level is low, body fat begins to accumulate, and weight increases. Chronic stress can also increase the level of cortisol, the so-called stress hormone, which also contributes to the deposition of fat.

Low levels of sexual desire can be caused by an increase or decrease in the test-ron, FSH and LH. All of them are interrelated and directly affect the reproductive system. Violation of at least one hormone almost always entails endocrine disruption and changes in the levels of other hormones.

Spermograms may also deteriorate, which can lead to infertility.

Not only disturbances in the production of sex hormones, but also a failure in the production of thyroid hormones can lead to erectile dysfunction (ED) in men.

High prolactin - a hormone that is responsible for the production of milk in women, can also cause hormonal imbalance in men. Prolactin is produced in the pituitary gland, problems associated with it (primarily the formation of prolactinomas) can cause ED.

A constant feeling of fatigue even after a night's rest and fast fatigue are among the most frequent symptoms of hormonal imbalance in men. First of all, such signs can be caused by improper production of thyroid hormones (hypothyroidism and hyperthyroidism), low T or elevated cortisol. The latter also regulates the sleep cycle, can lead to fatigue and weakness.

Low testosterone and hypothyroidism often cause such symptoms of hormonal disorders in men as depressed, sadness, mood swings, lack of motivation, depression. At the same time, all the listed symptoms, as a rule, become chronic.

Testosterone in the body of a man can turn into other molecules. The enzyme reductase converts it to dihydrotestosterone (DHT). This hormone is believed to be the main cause of age-related baldness. Because of it, hair growth slows down, and existing hair becomes thin and weak.

Hormonal imbalances in men can also often lead to an increase in estrogen (and a decrease in testosterone), an increase in prolactin and an increase in mammary glands (gynecomastia).

In case of hormonal imbalance, a man may experience any of these signs. The endocrine imbalance itself can be caused by both the natural aging process and the malfunctioning of the body.

HOW TO RESTORE THE HORMONAL BACKGROUND IN MEN

To normalize the hormones in a man by using replacement therapy with a test number. A male doctor and endocrinologist can write a prescription for a bioidentical testosterone cream, patch, or gel.

All forms of bioidentical testosterone have the same molecular structure and increase the level of free and total T in the blood. If a man chooses therapy with a test number (oral tablet, injection, subcutaneous implant, cream, gel or patch for topical use), he should take into account and be aware of the precautions:

  • such treatment cannot be prescribed for oneself, a full and comprehensive examination of the body should be carried out before the therapy,
  • besides testosterone, it may also be necessary to take other supplements or drugs (for example, aromatase inhibitors),
  • hormone replacement therapy can potentially worsen the condition in prostate cancer (or if there is a propensity to provoke it), therefore, before starting treatment, you should undergo a thorough examination, including rectal examination and screening for a specific prostate antigen (PSA). If a man has prostate cancer, testosterone treatment should be delayed.

A man who is undergoing a course of hormones (prescription drugs or other supplements) must consult a doctor and be regularly examined.

There is no one treatment option that would suit everyone, this is especially true when it comes to endocrine disorders. Restoring hormones is often a long and complicated process.

How to normalize hormonal background in men with natural methods

Men who do not want or cannot use hormone replacement therapy, after consulting with a physician, can replace medicines with vitamins and supplements aimed at reducing the effect of aging on the production and exchange of sex hormones. Below is a list of substances that, in combination, can normalize the hormonal background of a man, provided that he has serious pathologies.

  1. Essential nutrients to restore optimal testosterone production
  • Zinc

This mineral is involved in almost all aspects of the male reproductive system, including testosterone metabolism, sperm production and motility. A striking example of the utility of zinc is a study on 37 infertile men with a low test-on level and low sperm count associated with it. Men were given 60 mg of zinc daily for 45–50 days. In most patients, the T level rose significantly, and the average number of spermatozoa increased from 8 to 20 million. Some men require a higher level of zinc to adequately suppress aromatase.

Dehydroepiandrosterone is an important hormone, the amount of which decreases with age. In a 2006 study assessing DHEA intake in men aged 65, it was found that patients had a marked increase in testosterone and a significant decrease in low-density lipoprotein.

Tribulus terrestris, also known as Creeping Anchors, contains the active ingredient protodioscin, which is said to be converted into DHEA in the body. This explains Tribulus’s reputation as an aphrodisiac in Europe and Asia. Apparently, animal studies in 2003 and 2009. confirm the ability of tribulus to improve sexual function.

One of the reasons why testosterone production can be reduced is oxidative damage in the tissues that produce this hormone. In a study on the role of antioxidants in male hormonal imbalance in older men, it was noted that antioxidant supplements (including vitamins A and E, zinc and selenium) support the production of testosterone.

  1. Natural products that control aromatase and / or sex hormone binding globulin (SHBG)
  • Chrysin

The bioflavonoid chrysin (chrysin) is a natural aromatase inhibitor. Bodybuilders use it as a testosterone boosting supplement because it minimizes the conversion of the test to the female hormone estrogen. Although chrysin has low bioavailability, some sources state that it can be improved by taking black pepper extract (piperine) together.

The study showed that some ingredients in red wine (including quercetin) inhibit aromatase, which prevents the conversion of testosterone to estrogen.

  • Nettle root

The lignans contained in the nettle extract have the potential to help prevent the binding of SHBG to testosterone. It boosts free test-n, which is important for male sexual function. Nettle root extract is also widely used either in combination with with palmetto or by itself to relieve the symptoms of benign prostatic hyperplasia (BPH).

The researchers concluded that EPA (EPA) and DHA (DHA) fatty acids, found in omega-3, reduce the level of SHBG in middle-aged and elderly men.

Adequate protein intake is vital for maintaining muscle mass and normal testosterone levels. Scientists have established a link between diet and SHBG, as a result, it was found that a diet with a low protein content in men aged 40–70 years can lead to elevated levels of globulin and, consequently, a decrease in the biological activity of testosterone.

  1. Natural products to support sexual function
  • Muira Puama

Muira puama, Ptychopetalum olacoides, grows in the Amazon region of Brazil. It is considered an aphrodisiac and an effective treatment for impotence. In one of his experiments, men with low libido received 1.5 g of Puama muira a day for 2 weeks. 62% rated the treatment as having a dynamic effect, and 52% of those tested with erectile dysfunction rated the treatment as beneficial. In another study, 100 men and women aged 18 years and older were prescribed muira puama therapy with impotence and / or loss of desire. The frequency of sexual intercourse increased significantly in 66%. Of the 46 men who complained of loss of desire, 70% reported increased libido. Erection stability during intercourse was restored in 55% of men, and 66% noted a decrease in fatigue. Other reported positive effects included improvement in sleep and morning erection.

Maca has been used among indigenous peoples in the Andean region for centuries. This is a famous aphrodisiac and fertility enhancer. Peruvian researchers conducted a randomized, placebo-controlled, double-blind study for a small group of men aged 21–56 years.

The results showed that, compared with placebo, maca improved subjective indicators of male sexual desire.

The subjects consumed either 1500 mg, or 3000 mg of poppy or placebo for three months. Improvements were noted after eight weeks in those who took Maca.

L-carnitine is an amino acid derivative. It can be useful for older men who have sexual dysfunction and depression caused by androgen deficiency. Both testosterone and carnitine improve sexual desire and satisfaction, but carnitine is more effective than T in terms of improving erection, orgasm, and overall sexual well-being. L-carnitine is also more effective than a test for treating depression.

  1. Natural Prostate Health Products
  • Indole-3-carbinol (I3C)

Indole protects against the influence of dangerous estrogen metabolites and subsequent prostate cancer. Adequate intake of I3C from vegetables such as broccoli, Brussels sprouts, or supplements can be very helpful for mature and elderly men to control and reduce the risk of prostate cancer.

African cherry tree bark extract Pygeum africanum has been used in Europe for the treatment of BPH since 1960 and is currently the most frequently used therapeutic tool for this condition in France.

With palmetto (Serenoa repens) is widely used in Europe as a drug to reduce the symptoms of BPH. It has several mechanisms of action: suppression of 5-alpha reductase, inhibition of DHT binding to androgen receptors, reduction of the inflammatory component of prostate growth, induction of apoptosis and inhibition of prostate cell proliferation. Its clinical benefits with an enlarged prostate include a reduction in night urge, a decrease in the volume of residual urine in the bladder, and less discomfort during urination.

Symptoms of hormonal failure in adolescents

According to experts, the male hormonal background changes several times during the day, and this process is not considered a deviation. It can even cause feelings. Hormonal imbalance can occur not only among the representatives of the stronger sex of young and mature age, but also among adolescents 13-17 years old when puberty begins.

Characteristic signs of hormonal disorders during this period are:

  • excessive sweating - most often caused by the sympathetic nervous system, which is responsible for the activity of the sweat glands,
  • significant changes in behavior - a young person may be inclined to psychoemotional inconstancy, a calm state can abruptly be replaced by flashes of aggression,
  • deterioration of the epidermis due to the intensive work of the sebaceous glands. A face can become covered with acne and purulent acne, which will be very difficult to get rid of,

  • jumps in weight - with the same appetite, a young man can drastically lose weight or, conversely, add a few kilograms. Such changes are explained by the imbalance of glucocorticoids - substances that are produced by the adrenal glands,
  • delayed physical development - with a lack of growth hormone, the bone tissue will grow too slowly, and if it is abundant, gigantism can develop.

Hormonal failure in men at a young age can cause serious complications and affect the quality of later life. If testosterone levels are lowered, physical development may stop, and the following disorders will appear:

  • the voice will not change
  • lack of secondary sexual characteristics,
  • short stature,
  • breast augmentation.

If you delay puberty, you must immediately visit a specialist who will tell you what measures you need to take for further treatment.

Signs of hormonal disorders in men

In men of mature age, this pathology can manifest itself individually, depending on what it is provoked by (serious diseases or external factors). With a hormonal defect in men, the symptoms may be as follows:

  • if the pathology has arisen as early as adolescence, the patient may experience problems with sexual development,
  • the appearance of excess weight - the figure will begin to change and come closer to the female: the chest will increase in size, excess fat will appear on the stomach,
  • a decrease in libido or its complete absence, lethargy of erection,
  • disruptions in the nervous system (excessive irritability, mood swings, drowsiness, frequent depression and mood decline),

  • infertility,
  • increased fatigue and decreased physical endurance,
  • in some cases, there may be problems with the reproductive system - the patient may experience pain when urinating or suffer from incontinence,
  • cessation of facial hair growth, dry skin, hair loss and brittleness,
  • hoarseness
  • problems with the cardiovascular system,
  • tremor of the limbs.

The danger of such changes lies not only in the deterioration of the general condition, but also in possible problems with the conception of a child.

Diagnostics

How exactly will be treated depends on the diagnosis. Для выявления общей клинической картины эндокринолог не только осмотрит пациента визуально и проведет сбор анамнеза, но также назначит сдать определенные анализы и пройти некоторые исследования.

При диагностике оценивается состояние различных органов и функционирование систем организма:

  • cardiovascular system (vascular ultrasound, lipid profile detection, ECG),
  • mental activity (memory, concentration, emotional background),
  • endocrine system (blood sugar, testosterone, prolactin, LH, TT),

  • Ultrasound of the adrenal glands, kidneys, liver and thyroid gland,
  • X-ray of the skull (performed only if necessary)
  • radiograph of the musculoskeletal system and spine.

To understand exactly what the patient encountered, it is desirable to examine the body completely, only in this case, the chance of successful treatment will be high.

Therapy is selected on the basis of the obtained tests, the general condition and age of the patient, the presence of chronic diseases, as well as the original source that provoked the occurrence of pathologists.

The traditional method of treatment is aimed at normalizing the natural activity of the sex glands, restoring the functioning of the organs responsible for the distribution of sex hormones. To do this, it is prescribed to take certain medications that regulate the activity of the pituitary, thyroid and liver.

In order to speed up the process of recovery, the patient will need to follow certain recommendations:

  • to adhere to proper nutrition (rejection of fatty and fried foods, flour products and alcoholic beverages),
  • stay at home and, if possible, observe bed rest,
  • avoid stressful situations and experiences
  • reduce physical exertion
  • drink a course of multivitamins.

If the pathology is provoked by age-related changes, the patient needs to take medications containing testosterone all his life. Only in this way will it be possible to maintain the optimal level of hormones necessary for the proper functioning of the body.

Hormonal imbalance is an extremely serious pathology that is difficult to treat. Therefore, it would be much more sensible not to engage in recovery, but simply to prevent the development of the disease. To do this, you must adhere to an active lifestyle, eat right and avoid stressful situations.

What is a hormonal failure?

All life cycles of the human body are directly related to the physiological changes in the hormonal background, which ensure growth and reproduction, development and decay.

The value of the normal state of hormonal background is difficult to overestimate, because the endocrine system has a decisive influence on many functions of the central nervous system (emotions, feelings, memory, physical and intellectual performance), and also participates in the regulation of the work of all vital organs.

Initially, the "hormonal failure" was called the pathology of the endocrine system in women, which was clinically manifested, first of all, menstrual disorders.

Recently, however, the phrase "hormonal failure" has been increasingly used to designate various kinds of troubles associated with impaired endocrine regulation in men.

The fact is that, despite all the differences in the structure of the reproductive system, hormonal disorders cause both men and women many similar symptoms that have a systemic manifestation (central nervous system disorders, obesity, osteoporosis, the development of serious diseases of the cardiovascular system and etc.).

Causes of hormonal failure in women and men

The causes of hormonal disruptions in men and women are very diverse. First of all, it should be noted that hormones are the result of a complex interaction of the central neuroendocrine regulation system located in the brain (the so-called hypothalamic-pituitary system) and the endocrine glands located on the periphery (male and female sex glands).

So all the factors of hormonal failure in its origin can be divided into:
1. Causes associated with impaired central regulation.
2. Causes due to the pathology of peripheral glands (infectious-inflammatory diseases, congenital hypoplasia (underdevelopment), tumors, injuries, etc.).

Disruption of the hypothalamic-pituitary system, in turn, can be caused by its direct organic lesion (severe traumatic brain injury, tumor, encephalitis), or mediated by adverse external and internal factors (chronic fatigue syndrome, general exhaustion of the body, etc.) P.).

In addition, endocrine glands, which are not directly related to reproduction, have a strong effect on the general hormonal background. This is especially true for the adrenal cortex and thyroid gland.

Most hormones metabolized in the liver and excreted by the kidneys. Therefore, severe damage to these organs, leading to their failure, can also cause hormonal imbalances.

And finally, a hereditary factor is of paramount importance in the occurrence of hormonal disruptions. Especially strongly genetic predisposition is manifested in the development of climacteric disorders.

Most often, hormonal disruptions occur during periods when the endocrine system becomes particularly vulnerable due to physiological reasons. First of all, it concerns the period of puberty and the period of extinction of sexual function. In women, hormonal disruptions often develop during "hormonal storms" after abortions, as well as on the background of a complex restructuring of the body after childbirth.

A separate group consists of congenital disorders of the functioning of the system, providing a normal hormonal background. As a rule, such pathologies manifest themselves in the pubertal period by a delay or absence of the formation of secondary sexual characteristics.

Common symptoms of hormonal failure

Of course, the clinical picture of hormonal failure will strongly depend on the gender, age and general condition of the patient, as well as on the cause hormonal disorders. However, it is possible to isolate the symptoms characteristic of all cases of hormonal disorders.

The general symptoms of hormonal disruption can be divided into signs of inadequate functioning of the sexual sphere, the clinical picture of the disruption of the central nervous system and the symptoms of metabolic pathology.

Symptoms of hormonal disruption on the part of the reproductive system are impaired formation of secondary sexual characteristics (if we are talking about a teenager) or weakening of their severity, as well as the appearance of signs characteristic of the opposite sex (the so-called masculinization in women or feminization in men). In addition, various disorders of sexual and reproductive function develop:

  • decrease in libido, up to its complete extinction,
  • Erectile dysfunction in men
  • anorgasmia in women
  • infertility.

The clinical picture of the disturbance of the central nervous system during hormonal failure is manifested by the symptoms of the so-called cerebroscence (exhaustion):
  • irritability,
  • fast fatiguability,
  • drowsiness,
  • propensity for emotional weakness (tearfulness),
  • decrease in emotional background, down to depression,
  • in severe cases, a reversible deterioration in cognitive and intellectual abilities.

One of the main symptoms of metabolic disorders during hormonal disruption is an increase in body weight. So the sharp weight gain associated with sexual disorders is always suspicious of neuroendocrine disorders. Another characteristic symptom of hormonal failure is the development of osteoporosis (bone loss) due to a violation of calcium metabolism in the body.

It should be noted that all the above signs of hormonal failure are completely reversible. The activity of the nervous system, metabolism and bone structure are restored after the normalization of hormonal levels. However, a long-term hormonal imbalance can lead to more severe, irreversible complications from many body systems.

Hormonal disruptions leading to untimely puberty

Normally, puberty in girls begins at 7-8 years of age, and ends at 17-18. During this period, the most intensive growth and development of the whole organism occurs as a whole, secondary sexual characteristics are formed, the complex development of the female reproductive system occurs, ensuring the possibility of normal conception, childbirth and the birth of children.

In cases where the secondary sexual characteristics begin to appear earlier than 7-8 years, they say about premature puberty. In such girls, menstruation begins early (cases of the first menarche are described at 4 years), the mammary glands are enlarged, and the female physique is formed. Body growth accelerates, however, such girls are rarely above 150-152 cm, since as a result of premature puberty, growth of bone growth occurs in adolescence.

There are physiological (constitutional) and pathological premature puberty (PPS):
1. Constitutional PPP is a genetically determined early development that is not accompanied by any pathological symptoms. At the same time, an early matured girl is completely healthy and retains the ability for normal reproduction. Therefore, this type of PPS is not subject to treatment. It should be noted that with the constitutional PPP the first menarche is extremely rare before 6-7 years.
2. Pathological PPS can be of central origin or associated with hormone-producing ovarian tumors. The cause of PPS central genesis, as a rule, are tumors of the pituitary-hypothalamic system.

Delay of puberty (LPS) is indicated in cases where secondary sexual characteristics do not appear until the age of 16-17. Most often the delay in puberty is constitutional. In such cases, the first menstruation in a girl begins at the age of 17-18. At the same age, secondary sexual characteristics develop, and in the future, the sexual and endocrine systems function normally, ensuring the possibility of sex and the birth of children.

Pathological delay of sexual development may be associated with severe genetic diseases (Shereshevsky-Turner disease) or pathology of the pituitary gland - the center of endocrine regulation.

However, today the most common cause of hormonal disruption in adolescents, leading to a delay in sexual development, is alimentary exhaustion due to starvation (adherence to fashionable diets, anorexia nervosa, etc.).

Hormonal disruptions leading to sexual development with erased virilization

Sexual development with erased virilization is a pathological type of maturation, in which, along with female secondary sexual characteristics, there are some male (hair growth and development of a male-type skeleton). Such a hormonal failure is accompanied by symptoms of a metabolic disorder, such as obesity, juvenile acne, the appearance of stretch marks (stretch marks, like during pregnancy).

The cause of sexual development with latent virilization can be congenital disorders of the adrenal cortex or ovaries, due to genetic defects.

However, the most common hormonal failure of central genesis - hypothalamic syndrome of puberty (GSPPS).

The causes of GSPS are not fully disclosed. Most often, chronic foci of infection (tonsillitis), traumatic brain injuries, and emotional stresses lead to this pathology. There is evidence of the rapid development of hormonal disruption after acute viral infection in children prone to chronic overeating.

As a rule, a hormonal failure in SHIPS develops at the age of 11-13 years, immediately after the first menstruation. Such girls often have the appearance of health spirits: tall, overweight, broad shoulders and hips. However, the appearance is quite deceptive, since almost all patients have a number of disorders associated with the pathology of the autonomic nervous system. The instability of blood pressure with a tendency to hypertension, frequent headaches, increased fatigue, irritability are especially characteristic.

Another specific sign of GSPS is striae, which look like purple or (less often) pink stripes. These bands are transverse, their appearance is not associated with obesity (observed even in those rare cases when patients are not overweight), and indicates the activity of the process.

Dysfunctional uterine bleeding as a symptom of hormonal failure in girls during puberty

Dysfunctional uterine bleeding (DMC) is called menstrual disorders due to hormonal imbalance, accompanied by an increased blood flow. Hormonal failure in such cases occurs in the complex system of the hypothalamus-pituitary-ovaries.

MQD in girls during puberty are called juvenile uterine bleeding (UMC). This pathology is very common, accounting for more than 20% of diseases in pediatric and adolescent gynecology.

Causes of hormonal failure can be nervous or physical strain, acute infectious diseases, vitamin deficiency. According to statistics, practically healthy girls enrolled in intensive schedules (lyceums, gymnasiums, etc.) fall into the risk group.

Clinically, UMC is a uterine bleeding that develops in girls during puberty (usually within 2 years after the first menstruation), after the delay of the next menstruation for a period of two weeks to several months.

Such bleedings are usually abundant, and lead to marked anemia. Sometimes UMK are not abundant, but long (10-15 days).

Severe re-bleeding can be complicated by an imbalance between coagulation and anticoagulative blood systems (DIC), against which the bleeding is even more intense - this condition represents an immediate threat to life and requires emergency medical attention.

Signs of hormonal disruption in women of reproductive age

Prolonged absence of menstruation, not associated with pregnancy or lactation, in women of reproductive age is called amenorrhea, and indicates a hormonal failure.

According to the mechanism of occurrence are distinguished:
1. Amenorrhea central genesis.
2. Amenorrhea associated with dysfunction of the adrenal cortex.
3. Amenorrhea caused by ovarian pathology.

Severe mental trauma, as well as physical exhaustion caused by prolonged illness or nutritional factors (prolonged starvation) can lead to amenorrhea of ​​central genesis. In addition, it is possible to directly damage the hypothalamic-pituitary system in injuries, infectious-inflammatory or oncological processes.

In such cases, hormonal failure occurs on the background of nervous and physical exhaustion, and is accompanied by symptoms of bradycardia, hypotension, anemia.

Amenorrhea can also be one of the manifestations of Itsenko-Cushing syndrome. In such cases, hormonal imbalance leads to severe damage to many organs and systems. Patients have a very specific appearance: cushingoid obesity (moon-shaped purple-red face, fatty deposits on the neck and upper half of the body during atrophy of the muscles of the extremities), male-type hair growth, purple streaky striae on the body. In addition, arterial hypertension and osteoporosis are characteristic, and glucose tolerance is reduced.

Itsenko-Cushing syndrome indicates hyperproduction of adrenal cortex hormones, so that it can be caused by neoplasms secreting these hormones, or pituitary tumors that stimulate the synthesis of steroids in the adrenal glands.

However, the so-called functional hypercorticism (pseudo-Cushing syndrome) is quite common when functional disorders of the neuroendocrine system associated with obesity, alcoholism, and neuropsychological diseases become the cause of hormonal disruption.

The most common cause of ovarian amenorrhea is polycystic ovary syndrome (PCOS), which can occur under the influence of stress factors such as the onset of sexual activity, abortion, childbirth, etc. In addition to amenorrhea, the leading symptom of hormonal failure in PCOS is obesity, reaching second or third degree, as well as male-type hair growth (on the upper lip, chin, on the inner surface of the thighs). Very characteristic signs are also dystrophy of the skin and its appendages (stretch marks on the skin of the abdomen, chest and thighs, brittle nails, hair loss). In the future, disorders of lipid and carbohydrate metabolism develop - a tendency appears to develop atherosclerosis and type 2 diabetes.
More about amenorrhea

Dysfunctional uterine bleeding

Dysfunctional uterine bleeding in women of reproductive age occurs most often due to hormonal disruption caused by nervous or mental overstrain, infectious diseases, abortions, etc.

At the same time, the normal periodicity of the menstrual cycle is disturbed, and a predisposition to endometrial malignant neoplasms arises. The ability to conceive and normal childbearing in women with MQD is reduced.

В зависимости от наличия овуляции (выход яйцеклетки из фолликула в яичнике), различают овуляторные и ановуляторные ДМК. При овуляторных ДМК кровотечения, как правило, наступают после задержки менструации (6-8 недель и больше). At the same time, they often begin as moderate, but last a long time - sometimes strengthening, then weakening.

Anovulatory DMK develops against the background of a gradually lengthening cycle and, having begun, can be delayed for 1-1.5 months. The mechanism of occurrence of ovulatory and anovulatory DMK is different, therefore, for adequate treatment, laboratory diagnostics of the state of hormonal levels is necessary.

Premenstrual syndrome - the most common variant of hormonal failure in women of reproductive age

Premenstrual syndrome (PMS) is a complex of cyclically manifested symptoms associated with impaired normal regulation of hormonal levels in the hypothalamus.

This kind of hormonal failure most often occurs after 30 years, but it can also develop in young girls. The causes of PMS are not fully understood. Of great importance is genetic predisposition (often the family nature of the pathology is traced). The provoking factors are often abortions, severe nervous shocks, and infectious diseases.

Risk factors for PMS are stress and hypodynamia (living in big cities, intellectual work, sedentary lifestyle), as well as unhealthy diet, chronic gynecological diseases and central nervous system lesions (trauma, neuroinfection).

PMS gets its name from the time of occurrence: the symptoms appear a few days before the onset of menstruation, reach a maximum on the first day of menstruation, and completely disappear with the end. However, in severe cases, there is a progression of PMS - its duration increases, and the light intervals are reduced.

Conditionally, all the symptoms of PMS can be divided into several groups:
1. Neurosis-like disorders: irritability, tendency to depression, fast fatigue, sleep disturbance (daytime sleepiness and sleeplessness at night).
2. Migraine-like syndrome: severe headache, often accompanied by nausea and vomiting.
3. Signs of metabolic disorders (swelling of the face and extremities).
4. Symptoms of vegetative-vascular dystonia (lability of pulse and blood pressure, flatulence).

In severe cases, vegetative-vascular disorders occur according to the type of sympathoadrenal crises (unmotivated episodes of the fear of death, accompanied by an increase in blood pressure and an increase in heart rate, ending with abundant urination). Such crises indicate the involvement of the adrenal medulla in the process.

Most women complain of increased sensitivity to odors and painful engorgement of the mammary glands. Often there are violations of the various organs and systems (pain in the heart, a slight increase in body temperature, itchy skin, allergic manifestations).

Today, the list of symptoms of hormonal failure during PMS has exceeded 200 items, but psycho-emotional disorders are most common. At the same time, depression is more common in young women, and irritability is more common in mature women.
More about ICP

Hormonal failure in women after an abortion

Hormonal malfunction is one of the most frequent complications of abortion. It is caused both by a serious mental shock, and by the breakdown of a complex neuroendocrine restructuring of the body, which begins in the first weeks of pregnancy.

As a general rule, abortions in primiparous people are much more likely to have complications, regardless of how the pregnancy is terminated. Of course, the earlier the intervention was made, the lower the risk.

But if we are talking about medical abortion, then in this case, hormonal failure occurs already during the intervention itself. That is why, after a medical abortion, a course of hormonal therapy is required to restore the cycle.

Normally, the menstrual cycle should be restored a month after the abortion. If this does not happen, it is necessary to urgently consult a doctor.

In addition, the symptoms of hormonal failure after an abortion are:

  • weight gain
  • the appearance of stretch marks on the skin,
  • symptoms of the nervous system (irritability, headache, fatigue, depression),
  • the instability of blood pressure and pulse, sweating.

Hormonal failure in women after childbirth

After childbirth, a physiological reorganization of the organism takes place, which takes a sufficiently long period of time. Therefore, the timing of the restoration of the normal menstrual cycle is very variable, even in cases where a woman does not breastfeed.

Weight gain after childbirth during lactation is physiological - it is a side effect of hormones that stimulate milk production. Therefore, nursing women can only advise more to move, as well as to eliminate easily digestible high-calorie foods (sweets, baking, etc.). During lactation diet is contraindicated.

As a rule, after a period of feeding, the weight gradually decreases as hormonal levels return to normal.

If during the post-lactation period, despite nutritional restrictions and normal physical activity, the weight does not return to normal - one may suspect the presence of a hormonal failure.

Thus, it is necessary to consult a doctor in cases where the following symptoms are observed after childbirth and the end of the lactation period:

  • unmotivated weight gain
  • virilization signs (male-type hair growth),
  • irregular menstrual cycle, bloody bleeding between menstruation,
  • symptoms of neurosis (headaches, irritability, drowsiness, etc.).

Signs of hormonal failure in women during menopause

Climax is the period of attenuation of the reproductive function. In women, it occurs after 45 years, and continues until the end of life. Irregular menstruation in the period after 45 years is considered a physiological phenomenon, if they do not lead to severe bleeding and are not accompanied by any unpleasant symptoms. It should be noted that in many women, the cessation of menstruation occurs suddenly and painlessly.

However, the physiological extinction of reproductive function is less common today than the so-called menopausal syndrome - a symptom complex caused by hormonal disruption.

By the time of onset, all the symptoms of pathological menopause are divided into the following groups:
1. Early - appear two to three years before menopause (complete cessation of menstruation).
2. Delayed - develop over two to three years after menopause.
3. Late - occur five or more years after menopause.

Early signs include the most characteristic symptom of hormonal failure in menopausal syndrome - the so-called hot flashes, which are episodes of fever, especially strongly felt in the facial area.

Other early symptoms of pathological menopause are in many ways similar to signs of hormonal failure with premenstrual syndrome: psycho-emotional disturbances (irritability, depression, increased fatigue), vegetative-vascular pathology (palpitations, blood pressure lability, pain in the region of the heart), headaches resembling migraine.

Delayed symptoms are associated with a deficiency of female hormones - estrogen. Estrogen deficiency causes dystrophic damage to the skin and its appendages.

These processes are usually most pronounced in relation to the mucous membranes of the female genital organs, and lead to the development of a complex of urogenital disorders (vaginal dryness, lowering of its walls, pain during intercourse, discomfort during urination, urinary incontinence), in severe cases inflammatory processes (cystitis, vulvovaginitis).

In addition, it is often observed increased skin dryness, brittle nails, hair loss.

Late symptoms of hormonal failure in pathological menopause are signs of a gross violation of metabolic processes. The most characteristic are systemic osteoporosis, disorders of lipid metabolism (vascular atherosclerosis) and carbohydrate metabolism (reduced glucose tolerance, the development of type 2 diabetes).

The causes of hormonal disruptions in pathological climax are not fully understood. However, the proven value of genetic predisposition. As provoking factors, stress, malnutrition, physical inactivity, bad habits (smoking, frequent abuse of alcohol) are emitted.

At risk for the development of pathological menopause include women with the following pathologies:
1. Neuroendocrine disorders: premenstrual syndrome, toxicosis of pregnancy and dysfunctional uterine bleeding in history.
2. Diseases of the central nervous system: neuroinfections, neurosis, mental illness.
3. Gynecological pathologies: chronic inflammatory diseases of the pelvic organs, endometriosis.
4. Complicated obstetric history: abortion, miscarriage, difficult childbirth.

Causes of hormonal failure in men

Male sex hormones (androgens) are formed in the sex glands - the testes. Their products ensure the development of secondary sexual characteristics in boys, as well as tall stature, powerful muscles, aggressiveness.

Interestingly, for the normal functioning of the male body, female sex hormones (estrogens) are also needed, so the blood of a healthy man contains more estrogens than the blood of a woman during menopause.

Clinical studies have shown that it is estrogens that provide normal libido (sexual desire decreases with both excess and lack of female sex hormones in men). In addition, estrogen is responsible for the normal maturation of sperm and cognitive abilities, as well as affecting lipid metabolism. Another important function of estrogen is to ensure normal calcium metabolism in the bones.

Most of the estrogen in the male body is formed as a result of the transformation of testosterone in the liver and adipose tissue. Only a small percentage is synthesized directly in the gonads.

In men, as well as in women, the regulation of the activity of the sex glands is coordinated with the help of a complex hypothalamic-pituitary system.

Thus, hormonal disruptions in men can occur as a result of direct lesion of the testes (congenital anomalies, injuries, infectious and inflammatory processes, etc.) and in violation of the functioning of the hypothalamic-pituitary system. Accordingly, primary and secondary hypogonadism (primary and secondary failure of male sex hormone products) is distinguished.

Secondary hypogonadism (hormonal insufficiency of central genesis) in men occurs for the same reasons as in women (tumors of the hypothalamic-pituitary zone, trauma, neuroinfection, congenital malformations).

In addition, hormonal failure in men may be associated with increased estrogen production from testosterone. This often happens during chronic intoxication, when the androgen metabolism in the liver is disturbed, and their transformation into estrogens increases (chronic alcoholism, drug use, professional contact with certain poisons, radiation exposure).

More rarely, the failure of male hormones can be caused by endocrine pathologies (hyperthyroidism), hormone-active tumors, severe lesions of the liver and kidneys, occurring with intoxication (uremia, liver failure).

Puberty

Just like in women, in men there is an untimely (too early or too late) sexual development. Despite the differences in the structure of the sexes, the causes and symptoms of late development are similar.

Premature sexual development (CPD) in boys is usually associated with neoplasms of the hypothalamic-pituitary system. Also found constitutional early sexual development. With PPR, secondary sexual characteristics in boys appear up to 7-8 years old, there is increased growth, which suddenly stops in adolescence due to premature ossification of bone growth zones.

There are also false SPR associated with the pathology of the adrenal cortex. In such cases, it is combined with obesity and other signs of metabolic disorders. A similar clinical picture develops when eating foods that contain large amounts of hormones (milk and meat of animals that are stimulated with steroid drugs).

The delay in sexual development (CRA) in boys is indicated when development is delayed by more than two years, compared with the average periods. Hormone failure in such cases is most often associated with damage to the central nervous system (trauma, infection, intoxication, etc.), endocrine pathology (obesity, thyroid disease) or severe chronic diseases that lead to a general depletion of the body.

When making a diagnosis of CRA, differential diagnosis with hypogonadism (primary or secondary) should be made, as well as the possibility of constitutional CID (hereditary features of development in healthy children) should be taken into account.

Signs of hormonal failure in menopause in men

Normal in men, sexual function gradually decreases with age. However, this process is often accompanied by a number of pathological symptoms, the combination of which has been called the "menopausal syndrome in men."

In the pathological menopause in men, as well as in women, the symptoms of a violation of higher nervous activity come first:

  • irritability,
  • fast fatiguability,
  • mood lability with a tendency to depression,
  • tearfulness,
  • low self-esteem,
  • feeling of your own uselessness
  • panic attacks,
  • reduced cognitive and creative abilities.

Another characteristic symptom of pathological menopause in men is a sharp decrease in sexual function, which is accompanied by disorders of the urogenital system (painful urination, urinary incontinence, etc.).

Hormonal failure is manifested by symptoms characteristic of relative hyperestrogenemia: the mammary glands increase, there is a rapid weight gain with fat deposits on the female type (on the abdomen, hips, breasts), often the type of pubic hair growth resembles a female, the growth of hair on the face stops and decreases on the body.

Dystrophic changes of the musculoskeletal system are growing rapidly: osteoporosis, flabbiness and weakness of muscles develop, patients complain of pain in joints and bones.

Very characteristic violations of the cardiovascular system: pain in the heart, palpitations, developing hypertension and atherosclerosis.

The skin becomes dry and atrophic, brittle nails appear, hair falls out.

Violations of the vegetative-vascular system resemble the symptoms of female menopause: often hot flashes, excessive sweating.

The development of pathological menopause in men contribute to the transferred diseases of the central nervous system (traumatic brain injury, neuroinfection, intoxication), endocrine system pathologies (obesity, thyroid disease), liver disease, unhealthy lifestyle (hypodynamia, poor diet, alcohol abuse, smoking) .

Hormonal disruption can be provoked by a strong long-term nervous overstrain or a severe somatic disease. There is evidence of genetic susceptibility to the occurrence of hormonal disruptions. In addition, men who had hormonal disruptions in history (delayed sexual development, impaired sexual function during the reproductive period) fall into the risk group for the development of pathological menopause.

Treatment of hormonal failure

In cases where it is possible to radically eliminate the cause of hormonal disruption (a hormone-producing tumor), etiological treatment is carried out.

If the cause is unremovable (menopausal syndrome, primary hypogonadism), according to the indications, hormone replacement therapy is prescribed.

Hormonal disruptions in women and men of the reproductive period are often able to be corrected by the course prescription of hormonal drugs, in cases where they are not caused by serious organic pathology.

Of great importance in the treatment and prevention of hormonal disruptions in women and men has a healthy lifestyle:

  • correct day regimen
  • healthy food
  • metered exercise,
  • getting rid of addictions (smoking, alcoholism, drug use),
  • prevention of stress reactions.

According to the indications, vitamin therapy, phytotherapy, physiotherapy, and spa treatment are carried out.

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